Frequency-dependent nanomechanical profiling for medical diagnosis

• Santiago D. Solares and
• Alexander X. Cartagena-Rivera

Beilstein J. Nanotechnol. 2022, 13, 1483–1489, doi:10.3762/bjnano.13.122

• nanomechanical measurements into medical diagnosis, which includes specialized in vivo sensing, computer analysis (AFM force spectroscopy analysis), communication with the healthcare provider, and mining of the aggregate community database. Given the mechanical nature of AFM, the above strategy naturally fits

Temperature and chemical effects on the interfacial energy between a Ga–In–Sn eutectic liquid alloy and nanoscopic asperities

• Yujin Han,
• Pierre-Marie Thebault,
• Corentin Audes,
• Xuelin Wang,
• Haiwoong Park,
• Jian-Zhong Jiang and
• Arnaud Caron

Beilstein J. Nanotechnol. 2022, 13, 817–827, doi:10.3762/bjnano.13.72

• atomic force microscopy (AFM) tips of different chemistries as a function of the temperature (T = 21–90 °C) by AFM force spectroscopy using an XE100 AFM equipped with a heating stage (manufactured by Park Instruments, Republic of Korea). We recorded force–distance curves with PtSi-coated Si cantilevers

Bulk chemical composition contrast from attractive forces in AFM force spectroscopy

• Dorothee Silbernagl,
• Media Ghasem Zadeh Khorasani,
• Natalia Cano Murillo,
• Anna Maria Elert and
• Heinz Sturm

Beilstein J. Nanotechnol. 2021, 12, 58–71, doi:10.3762/bjnano.12.5

• determined. Keywords: AFM force spectroscopy; composites; principle component analysis; structure–property correlation; van der Waals forces; Introduction The mechanical properties of small volumes of materials can be measured using various atomic force microscopy (AFM) methods. The well-established force

• for this task, a high-resolution method of AFM force spectroscopy was used, which is called intermodulation AFM. This dynamic method is able to scan the sample with a resolution comparable to the tapping-mode images, producing the equivalent of a FDC at each pixel. A 2 × 2 µm topography scan of the

• future studies, by correlating more than two parameters, a fully automated PCA of AFM force spectroscopy data can be pursued. Experimental All force spectroscopy measurements were performed with a MFP-3D Asylum instrument (Oxford Instruments Asylum Research Inc., Santa Barbara, CA, USA). AFM FDCs were

Probing fibronectin–antibody interactions using AFM force spectroscopy and lateral force microscopy

• Andrzej J. Kulik,
• Małgorzata Lekka,
• Kyumin Lee,
• Grazyna Pyka-Fościak and
• Wieslaw Nowak

Beilstein J. Nanotechnol. 2015, 6, 1164–1175, doi:10.3762/bjnano.6.118

Modification of a single-molecule AFM probe with highly defined surface functionality

• Fei Long,
• Bin Cao,
• Ashok Khanal,
• Shiyue Fang and
• Reza Shahbazian-Yassar

Beilstein J. Nanotechnol. 2014, 5, 2122–2128, doi:10.3762/bjnano.5.221

• Information File 1). The slides were washed with DMF, CHCl3, MeOH, and dried in a stream of argon. After each modification process, the probe and substrate surfaces were characterized with FTIR and contact angle measurements. As shown in Figure S4 and Table S1 in Supporting Information File 1. AFM force

• spectroscopy experiment Single-molecule probe modification: The alkyne-modified probe was engaged to the Cu substrate in contact mode with 1 nN force in 0.05 M azide solution. The average surface roughness Ra of the Cu surface was 1.33 ± 0.24 nm determined through AFM topography (shown in Figure S8, Supporting

Hydrophobic interaction governs unspecific adhesion of staphylococci: a single cell force spectroscopy study

• Nicolas Thewes,
• Peter Loskill,
• Philipp Jung,
• Henrik Peisker,
• Markus Bischoff,
• Mathias Herrmann and
• Karin Jacobs

Beilstein J. Nanotechnol. 2014, 5, 1501–1512, doi:10.3762/bjnano.5.163

• hydrophobic (hydrophilic) surfaces. Keywords: atomic force microscopy (AFM); force spectroscopy; hydrophobic interaction; single cell; Staphylococcus carnosus; Introduction Members of the genus Staphylococcus are known to form extremely resistant biofilms, some of which can cause severe infectious diseases

• AFM force spectroscopy experiments with bacterial cells, both types of surfaces were immersed in PBS buffer. Bacteria For the experiments, freshly prepared exponential phase S. carnosus strain TM300 cells were used [4]. The bacteria were cultured on blood agar plates and transferred into 5 mL of TSB

• demonstrate that force/distance measurements are characteristic for the individual bacterial probe and are therefore most suitable to characterize bacterial adhesion. Next, we explore the influence of the AFM force spectroscopy parameters on the force/distance curves. The tip (or rather the piezo drive

Calibration of quartz tuning fork spring constants for non-contact atomic force microscopy: direct mechanical measurements and simulations

• Jens Falter,
• Marvin Stiefermann,
• Gernot Langewisch,
• Philipp Schurig,
• Hendrik Hölscher,
• Harald Fuchs and
• André Schirmeisen

Beilstein J. Nanotechnol. 2014, 5, 507–516, doi:10.3762/bjnano.5.59

• result is that even these sensors show a significantly high spread of kqPlus = 1480–1708 N/m, which demonstrates the need to calibrate each individual sensor that is used for quantitative nc-AFM force spectroscopy measurements. FEM simulations Special care was taken to make the geometric model of the

Exploring the complex mechanical properties of xanthan scaffolds by AFM-based force spectroscopy

• Hao Liang,
• Guanghong Zeng,
• Yinli Li,
• Shuai Zhang,
• Huiling Zhao,
• Lijun Guo,
• Bo Liu and
• Mingdong Dong

Beilstein J. Nanotechnol. 2014, 5, 365–373, doi:10.3762/bjnano.5.42

• suggests complicated intermolecular interactions among xanthan fibrils. The results provide crucial information to understand the structures and mechanical properties of the xanthan scaffold. Keywords: atomic force microscopy (AFM); force spectroscopy (FS); mechanical properties; xanthan scaffold